"People in covfefe houses shouldn't throw covfefe", she wrote in a brief message. "I had to inject money into it - the DNC - to keep it going".
Her comments drew swift rebuttals from some Democratic operatives who built, or worked with, that data.
Clinton was widely projected by pundits and pollsters to win the November 2016 election, but ultimately fell to President Trump after he made surprise wins in key states such as Pennsylvania, Wisconsin and MI.
"DNC data folks: today's accusations are fucking bullshit, and I hope you understand the good you did despite that nonsense", he tweeted.
David Radloff, the co-founder of the Democratic data and analytics firm Clarity Campaign Labs, tweeted: "Used DNC data on numerous campaigns this year, well managed, efficient, accurate".
The biggest question is what is Clinton's end game?
"I think this time around, the confluence of the Russian Federation hacking and that they tried to sway the election Trump's way. and the Comey thing gave her back-up to say, 'Hey, this wasn't my fault, '" the ex-adviser said.
A source that was close to the Clinton campaign said the campaign relied too much on data. "Who told them? Who were they coordinating with, or colluding with?" "That had nothing to do with the data they got".
The Democrats need to be focusing on the future, a former DNC aide said in a report by The Hill. I inherit nothing from the Democratic Party. "Data is a tool for campaigns, not a strategy".
That element of the campaign - analytics - is built on top of the party-provided data.
"It's always healthy whether you win or lose to do some introspection on what went right and what went wrong".
Still, there were elements of Clinton's argument that are hard to dispute. The DNC Chair Debbie Wasserman Schultz had to resign after Wikileaks revealed that she was trying to rig the nomination contest in favour of Ms. Clinton. "Her team thought they knew better".
When asked why she didn't visit Wisconsin or other states that Trump won, Clinton blamed the DNC's bad information.
"Put yourself in the position of a low-information voter", she said, "and all of a sudden your Facebook feed, your Twitter account is saying, 'Oh my gosh, Hillary Clinton is running a child trafficking operation in Washington with John Podesta!" She likened the president's strategy to that of leaders in Bosnia and Rwanda who enflamed cultural tensions to win power.
"That is incredibly unsafe", she said.